SEC Form 4 · Updated Daily
OPK
— OPKO HEALTH, INC. OwnershipInsider and institutional ownership derived from SEC Form 4 filings. Click any owner to see their holdings across every company they’ve filed on, and how their position has changed over time.
Current Reporting Owners
| Owner | Role | Shares Owned | As Of | Last Activity |
|---|---|---|---|---|
| FROST PHILLIP MD ET AL | 10%+ Owner | 216,706,448 | 2025-11-21 | P |
| Frost Gamma Investments Trust | 10%+ Owner | 216,706,448 | 2025-11-21 | P |
| Rubin Steven D | Director | 6,571,966 | 2026-07-24 | F |
| Logal Adam | Officer | 563,396 | 2026-07-24 | F |
| PAGANELLI JOHN A | Director | 394,340 | 2026-03-20 | P |
Recent Filings
| Date | Owner | Activity | Shares | Price | Owned After |
|---|---|---|---|---|---|
| 2026-07-24 | Rubin Steven D | Tax withholding | 53,266 | $1.22 | 6,571,966 |
| 2026-07-24 | Logal Adam | Tax withholding | 53,266 | $1.22 | 563,396 |
| 2026-06-18 | Yu Alice Lin-Tsing | Grant / award (derivative) | 30,000 | $0.00 | 30,000 |
| 2026-06-18 | UPPALURI SUBBARAO V | Grant / award (derivative) | 80,000 | $0.00 | 80,000 |
| 2026-06-18 | PFENNIGER RICHARD C JR | Grant / award (derivative) | 60,000 | $0.00 | 60,000 |
| 2026-06-18 | PAGANELLI JOHN A | Grant / award (derivative) | 30,000 | $0.00 | 30,000 |
| 2026-06-18 | MEDEL ROGER MD | Grant / award (derivative) | 30,000 | $0.00 | 30,000 |
| 2026-06-18 | Lachman Prem A | Grant / award (derivative) | 30,000 | $0.00 | 30,000 |
| 2026-03-20 | PAGANELLI JOHN A | Open-market buy | 10,000 | $1.14 | 394,340 |
| 2026-03-18 | UPPALURI SUBBARAO V | Grant / award (derivative) | 50,000 | $0.00 | 50,000 |
| 2025-11-21 | Frost Gamma Investments Trust | Open-market buy | 192,870 | $1.33 | 216,706,448 |
| 2025-11-21 | Frost Gamma Investments Trust | Open-market buy | 191,490 | $1.33 | 216,513,578 |
| 2025-11-21 | Frost Gamma Investments Trust | Open-market buy | 89,375 | $1.32 | 216,322,088 |
| 2025-11-21 | Frost Gamma Investments Trust | Open-market buy | 3,894 | $1.32 | 216,232,713 |
| 2025-11-21 | Frost Gamma Investments Trust | Open-market buy | 102,371 | $1.30 | 216,228,819 |
| 2025-11-21 | FROST PHILLIP MD ET AL | Open-market buy | 192,870 | $1.33 | 216,706,448 |
| 2025-11-21 | FROST PHILLIP MD ET AL | Open-market buy | 191,490 | $1.33 | 216,513,578 |
| 2025-11-21 | FROST PHILLIP MD ET AL | Open-market buy | 89,375 | $1.32 | 216,322,088 |
| 2025-11-21 | FROST PHILLIP MD ET AL | Open-market buy | 3,894 | $1.32 | 216,232,713 |
| 2025-11-21 | FROST PHILLIP MD ET AL | Open-market buy | 102,371 | $1.30 | 216,228,819 |
| 2025-11-20 | Frost Gamma Investments Trust | Open-market buy | 13,664 | $1.35 | 216,126,448 |
| 2025-11-20 | Frost Gamma Investments Trust | Open-market buy | 1,757 | $1.34 | 216,112,784 |
| 2025-11-20 | Frost Gamma Investments Trust | Open-market buy | 24,579 | $1.34 | 216,111,027 |
| 2025-11-20 | Frost Gamma Investments Trust | Open-market buy | 161,818 | $1.33 | 216,086,448 |
| 2025-11-20 | Frost Gamma Investments Trust | Open-market buy | 211,948 | $1.33 | 215,924,630 |
| 2025-11-20 | Frost Gamma Investments Trust | Open-market buy | 47,105 | $1.32 | 215,712,682 |
| 2025-11-20 | Frost Gamma Investments Trust | Open-market buy | 119,129 | $1.32 | 215,665,577 |
| 2025-11-20 | FROST PHILLIP MD ET AL | Open-market buy | 13,664 | $1.35 | 216,126,448 |
| 2025-11-20 | FROST PHILLIP MD ET AL | Open-market buy | 1,757 | $1.34 | 216,112,784 |
| 2025-11-20 | FROST PHILLIP MD ET AL | Open-market buy | 24,579 | $1.34 | 216,111,027 |
| 2025-11-20 | FROST PHILLIP MD ET AL | Open-market buy | 161,818 | $1.33 | 216,086,448 |
| 2025-11-20 | FROST PHILLIP MD ET AL | Open-market buy | 211,948 | $1.33 | 215,924,630 |
| 2025-11-20 | FROST PHILLIP MD ET AL | Open-market buy | 47,105 | $1.32 | 215,712,682 |
| 2025-11-20 | FROST PHILLIP MD ET AL | Open-market buy | 119,129 | $1.32 | 215,665,577 |
| 2025-11-19 | Frost Gamma Investments Trust | Open-market buy | 155,496 | $1.32 | 215,546,448 |
| 2025-11-19 | Frost Gamma Investments Trust | Open-market buy | 198,904 | $1.31 | 215,390,952 |
| 2025-11-19 | Frost Gamma Investments Trust | Open-market buy | 66,504 | $1.31 | 215,192,048 |
| 2025-11-19 | Frost Gamma Investments Trust | Open-market buy | 12,993 | $1.30 | 215,125,544 |
| 2025-11-19 | Frost Gamma Investments Trust | Open-market buy | 30,082 | $1.30 | 215,112,551 |
| 2025-11-19 | Frost Gamma Investments Trust | Open-market buy | 21,236 | $1.29 | 215,082,469 |
Source: SEC EDGAR Form 4 filings. For informational purposes only — not investment advice.